The Purification of Glucose Type Glycosyl Nitrate and The Synthesis of Spacer-Armed N-Acetyllactosamines and Their Dimers

Authors

Qin Li, Peking University
Hui Li, Peking University
Bin Su, Cleveland State UniversityFollow
Xiang Bao Meng, Peking University
Meng Shen Cai, Peking University
Zhong Jun Li, Peking University

Document Type

Article

Publication Date

2002

Publication Title

Chinese Chemical Letters

Abstract

3, 6-di-O-acetyl-4-O-(2, 3, 4, 6-tetra-O-acetyl-beta-D-galactopyranosyl)-2-azido-2-deoxy-beta-D-glucoppyranosyl nitrate could be separated from its mannose type isomer by glycosylation according to the reactivity difference of these two compounds. The pure glucose type nitrate can be converted to corresponding trichloroacemidate, which reacted with spacer arms in solution of CH2Cl2 with BF3.Et2O as promoters to give desired glycosides and dimers.

Recommended Citation

Li, Qin; Li, Hui; Su, Bin; Meng, Xiang Bao; Cai, Meng Shen; and Li, Zhong Jun, "The Purification of Glucose Type Glycosyl Nitrate and The Synthesis of Spacer-Armed N-Acetyllactosamines and Their Dimers" (2002). Chemistry Faculty Publications. 456.
https://engagedscholarship.csuohio.edu/scichem_facpub/456

Volume

13

Issue

4