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Description

Telomeres are DNA-protein complexes located at the ends of linear chromosomes. Acting like a cap, they protect chromosome ends from degradation and rearrangement, maintaining genomic stability. Our lab has identified several T. brucei telomere proteins, including TRF (TTAGGG Repeat-binding Factor), TIN2 (TRF1-interacting Nulcear Protein 2) and RAP1 (Repressor Activator Protein 1) homologs. We are currently verifying the interactions between the new candidates and TbTIN2 or TbRAP1.

Publication Date

9-6-2012

Disciplines

Genetics and Genomics | Genomics | Life Sciences

Comments

Student Researcher: Miao Wang; Fan Wu

Faculty Advisor: Bibo Li, Ph.D.

Yeast 2-Hybrid Screen for T. Brucei TIN2- and RAP1- Intracting Proteins

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Genomics Commons

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