© 2019 The Authors Recent advances in human induced pluripotent stem cell-derived cardiomyocytes (iPSCM) field offer a novel platform for modeling cardiac metabolism, heart diseases drug candidates screening and cardiac toxicity assessments. These workflows require a fully functional characterization of iPSCMs. Here we report a step by step protocol for iPSCM metabolic characterization. The described assays cover analysis of small metabolites involved in a vital metabolic pathways.
House, Alisha; Fatica, Erica; Shah, Rohan; Stergar, Jared; Pearce, Ryan; and Sandlers, Yana, "A Protocol for Metabolic Characterization of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (iPS-CM)" (2020). Chemistry Faculty Publications. 545.
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