Abstract or Poster Image (217 KB)
Telomeres are DNA-protein complexes located at the ends of linear chromosomes. Acting like a cap, they protect chromosome ends from degradation and rearrangement, maintaining genomic stability. Our lab has identified several T. brucei telomere proteins, including TRF (TTAGGG Repeat-binding Factor), TIN2 (TRF1-interacting Nulcear Protein 2) and RAP1 (Repressor Activator Protein 1) homologs. We are currently verifying the interactions between the new candidates and TbTIN2 or TbRAP1.
Genetics and Genomics | Genomics | Life Sciences
Wang, Miao and Wu, Fan, "Yeast 2-Hybrid Screen for T. Brucei TIN2- and RAP1- Intracting Proteins" (2012). Undergraduate Research Posters 2012. 45.