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Description

Lecithin cholesterol acyltransferase (LCAT) is a plasma enzyme that remodels nascent high density lipoprotein (HDL) into a mature form called spherical HDL. The model will be used in the future to map the amino acid residues from LCAT and the protein component of nascent HDL (apoA1) involved in mutual interaction, and to identify LCAT residues interacting with the lipid phase of nascent HDL.

Publication Date

9-6-2012

Disciplines

Chemicals and Drugs | Enzymes and Coenzymes | Medicine and Health Sciences

Comments

Student Researcher: Christopher Pechura

Faculty Advisor: Valentin Gogonea

Key Players in Reverse Cholesterol Transport: The Plasma Enzyme LCAT

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