Oriented Immobilized Sialyloligo-macroligand Microarray
Contribution to Books
Macro-Glycoligands: Methods and Protocols
Silaic acid is the most common terminal glycan on cell surface glycoproteins and glycolipids, involving in many biological processes. Studying interactions between multivalent sialic acid scaffolds and proteins binding to it will give incredible information in understanding the biological process the sialic acid is involved in. Here we describe chemoenzymatic synthesis of chain-end functionalized sialyllactose-containing glycopolymers with different linkages and their oriented immobilization for glycoarray and SPR-based glyco-biosensor applications.
Narla, S. N.; Sun, X. Oriented Immobilized Sialyloligo-macroligand Microarray. In Macro-Glycoligands: Methods and Protocols; Sun, X., Ed.; Springer New York: New York, NY, 2016; pp 195-206.