Recent Advances in the Synthesis and Biomedical Applications of Chain-End Functionalized Glycopolymers
Journal of Carbohydrate Chemistry
Glycopolymers as multivalent clusters of carbohydrate derivatives have been proven effective tools in the study of carbohydrate-based biological processes and have shown great potential in biomedical applications. It has been found that the shape and size of glycopolymers, as well as the density and relative positioning of their glycan appendages, are very important regarding their effectiveness in bio-interactions. Recently, a variety of chain-end functionalized polymers have been explored for the preparation of structurally well-defined glycopolymers that have potential protein modification and microarray fabrication applications. This review summarizes recent advances in the synthesis and biomedical applications of chain-end functionalized glycopolymers.[
Narla, Satya Nandana; Nie, Huan; Li, Yu; and Sun, Xue-Long, "Recent Advances in the Synthesis and Biomedical Applications of Chain-End Functionalized Glycopolymers" (2012). Chemistry Faculty Publications. 44.