Title
Single Nucleotide Polymorphisms : Methods and Protocols
Files
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Description
In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible for phenotypic differences between individuals, and have been suggested to affect the development of diseases in humans and the response to drug treatment and environmental stress. In Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition, expert researchers explore the latest advances in this area, highlighting the substantial progress that has been made in SNP genotyping, examining recent developments in high-throughput genotyping approaches, and exploring our new understanding of the impact of SNPs on gene function. Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.
ISBN
9781603274104
Publication Date
10-28-2009
Publisher
Humana Press
City
New York
Disciplines
Analytical, Diagnostic and Therapeutic Techniques and Equipment | Genetic Processes | Medicine and Health Sciences
Recommended Citation
Komar, Anton A., "Single Nucleotide Polymorphisms : Methods and Protocols" (2009). Biological, Geological, and Environmental Department Books. 6.
https://engagedscholarship.csuohio.edu/scibges_bks/6
