Sequence Analysis of the Rhop-3 Gene of Plasmodium yoelii
Journal of Eukaryotic Microbiology
The 110 kDa/Rhop-3 rhoptry protein of Plasmodium falciparum is non-covalently associated with two other proteins, the 140 kDa Rhop-1 and the 130 kDa Rhop-2. cDNAs encoding Rhop-3 from Plasmodium yoelii were isolated using rhoptry-specific antisera from Plasmodium falciparum, P. yoelii, and Plasmodium chabaudi. The cDNAs encoded peptides with partial homology to the C-terminal region (residues 541-861) of P. falciparum Rhop-3. Core regions of homology to the P. falciparum gene will be useful in determining the biological role of Rhop-3 and its potential as a vaccine candidate for malaria.
Anthony, Robert N.; Yang, Jiacheng; Krall, Jennifer A.; and Sam-Yellowe, Tobili Y., "Sequence Analysis of the Rhop-3 Gene of Plasmodium yoelii" (2000). Biological, Geological, and Environmental Faculty Publications. 198.