Document Type
Article
Publication Date
9-3-2008
Publication Title
Cancer Chemotherapy and Pharmacology
Disciplines
Cancer Biology | Cell and Developmental Biology | Life Sciences
Abstract
Ovarian cancer is the leading cause of death among all gynecological malignancies in Western countries. Although therapy for ovarian cancer has been greatly improved in the past 20 years, the overall survival for patients with advanced ovarian cancer has not changed signiWcantly. The poor survival rates in patients with advanced ovarian cancer are due both to late diagnosis and to lack of eVective drugs for the majority of patients who have a relapse and develop resistance to current chemotherapy agents used for ovarian cancer. Thus, developing and discovering eVective novel drugs with diVerent molecular structures from conventional chemotherapy agents have become an urgent clinical need.
DOI
10.1007/s00280-008-0830-7
Version
Postprint
Publisher's Statement
© Springer-Verlag 2008
Recommended Citation
Liu, H., Liang, S., Kumar, S., Weyman, C. M., Liu, W., , & Zhou, A. (2009). Statins induce apoptosis in ovarian cancer cells through activation of JNK and enhancement of Bim expression. Cancer Chemotherapy and Pharmacology, 63(6), 997 - 1005. doi:10.1007/s00280-008-0830-7
Volume
63
