Direct Electron Transfer to The Oxygenase Domain of Neuronal Nitric Oxide Synthase (NOS): Exploring Unique Redox Properties of NOS Enzymes
Document Type
Article
Publication Date
10-13-2004
Publication Title
Journal of The American Chemical Society
Abstract
Thin film direct electrochemistry shows that the oxygenase domain of neuronal nitric oxide synthase undergoes reversible electron transfer with an underlying electrode. The midpotential of the FeIII/FeII couple is found to be modulated by both the binding of the tetrahydropterin cofactor and the pH of the buffer medium.
Recommended Citation
Bayachou, Mekki and Boutros, Jean A., "Direct Electron Transfer to The Oxygenase Domain of Neuronal Nitric Oxide Synthase (NOS): Exploring Unique Redox Properties of NOS Enzymes" (2004). Chemistry Faculty Publications. 342.
https://engagedscholarship.csuohio.edu/scichem_facpub/342
DOI
10.1021/ja0482987
Volume
126
Issue
40
Comments
This research is supported by the U.S. DOE-BES through a grant of the “ Catalysis Science ” program to M.B. (DE- FG02-03ER15462).