Document Type
Article
Publication Date
1-31-2003
Publication Title
Carbohydrate Research
Abstract
Anomers of monovalent and divalent β-d-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-d-gluco-pyranosides were synthesized under different glycosylation conditions, and evaluated for in vitro antimetastatic activity. Three compounds showed promising inhibitory effects on cancer cell attachment, spreading, migration, and invasion. Six divalent O-β-d-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-d-glucopyranosides (29–34) were synthesized and their antimetastatic activities were studied.
Recommended Citation
Li, Qin; Su, Bin; Li, Hui; Meng, Xiang Bao; Cai, Meng Shen; Li, Zhong Jun; Zhou, Rou Li; and Suo, Ta Lin, "Synthesis and Potential Antimetastatic Activity of Monovalent and Divalent β-D-Galactopyranosyl-(1→4)-2-Acetamido-2-Deoxy-D-Glucopyranosides" (2003). Chemistry Faculty Publications. 419.
https://engagedscholarship.csuohio.edu/scichem_facpub/419
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
DOI
10.1016/S0008-6215(02)00438-X
Version
Postprint
Volume
338
Issue
3
