Chemically-Selective Surface Glyco-Functionalization of Liposomes Through Staudinger Ligation
Document Type
Article
Publication Date
5-22-2009
Publication Title
Chemical Communications
Abstract
An efficient and chemoselective liposome surface glyco-functionalization method has been developed based on Staudinger ligation, in which the carbohydrate derivative carrying an azide spacer is conjugated onto the surface of preformed liposomes bearing a terminal triphosphine in PBS buffer (pH 7.4) at room temperature.
Recommended Citation
Zhang, H.; Ma, Y.; Sun, X. Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation. Chemical Communications 2009, 2009, 3032-3034.
DOI
10.1039/b822420j
Issue
21
Comments
The authors acknowledge financial support under grants from American Health Assistance Foundation (AHAF-H2007027) and the Startup Fund from Cleveland State University.