Trimethyllysine, a Trimethylamine N-oxide Precursor, Provides Near- and Long-term Prognostic Value in Patients Presenting with Acute Coronary Syndromes

Authors

Xinmin S. Li, Cleveland Clinic
Slayman Obeid, University Hospital Zurich
Zeneng Wang, Cleveland Clinic
Benjamin J. Hazen, Cleveland Clinic
Lin Li, Cleveland Clinic
Yuping Wu, Cleveland State UniversityFollow
Alex G. Hurd, Cleveland Clinic
Xiaodong Gu, Cleveland Clinic
Alan Pratt, Cleveland Clinic
Bruce S. Levison, Cleveland Clinic
et. al.
Stanley Hazen, Cleveland ClinicFollow

Document Type

Article

Publication Date

8-21-2019

Publication Title

European Heart Journal

Abstract

Trimethyllysine (TML) serves as a nutrient precursor of the gut microbiota-derived metabolite trimethylamine Noxide (TMAO) and is associated with incident cardiovascular (CV) events in stable subjects. We examined the relationship between plasma TML levels and incident CV events in patients presenting with acute coronary syndromes (ACS).

Repository Citation

Li, Xinmin S.; Obeid, Slayman; Wang, Zeneng; Hazen, Benjamin J.; Li, Lin; Wu, Yuping; Hurd, Alex G.; Gu, Xiaodong; Pratt, Alan; Levison, Bruce S.; al., et.; and Hazen, Stanley, "Trimethyllysine, a Trimethylamine N-oxide Precursor, Provides Near- and Long-term Prognostic Value in Patients Presenting with Acute Coronary Syndromes" (2019). Mathematics and Statistics Faculty Publications. 319.
https://engagedscholarship.csuohio.edu/scimath_facpub/319

DOI

10.1093/eurheartj/ehz259

Volume

40

Issue

32