Undergraduate Research Posters 2018

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  Effects of greater palatine nerve anesthesia on the activity of hyoid musculature during swallowing

  Besa Bunjaku

  Feeding is an important activity for all animals. An expansive array of sensory provide information to the brain about food handling during feeding. The brain then coordinates muscles to push the bolus into the esophagus, bypassing the airway. Previous work shows considerable coordination among sensor arrays and the nerves supplying them. Therefore it is likely that anesthetizing part of the oral cavity (in this case, the tissue covering the hard palate) will cause changes in the timing of muscles that are active during swallowing, even though these muscles are supplied ... Read More

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  Balance Training Using the Multi-directional Harness System

  Araxie Demirjin and Kristy Tachji

  Introduction and Purpose Individuals post-stroke frequently have impairments in balance and mobility. This study aims to increase mobility through high intensity balance training in a multi-directional harness system using video gaming to add environmental and tsk complexity. We hypothesize the training will improve balance, mobility, and decrease falls. Methods In this case series, two adults post-stroke completed seven sessions of balance training using four adapted commercial video games from the X-Box Kinect™ (20,000 Leaks (L), Reflex Ridge (R), Table Tennis (T), and Target Kick (K)) on varied types of floor ... Read More

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  The T.E.A.M Approach to Interprofessional Education for Pre-Professional and Professional Health Students

  Mary C. Sammon and Hayden A. Parente

  Interprofessional education (IPE) is defined as “students from two or more professions learning about, from and with each other to enable effective collaboration and improve health outcomes” (World Health Organization, 2010). When used effectively, IPE programs aid in preparing pre-professional undergraduate and graduate health professional students to enter the healthcare field as effective team members, who are knowledgeable in delivering quality, collaborative care. This project aimed to 1) assess the impact of current IPE programming, 2) create an evidence-based framework to develop IPE programming and 3) determine if current evaluative ... Read More

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  Reading-related phonological processing interventions for individuals who use augmentative and alternative communication (AAC): A systematic review of the research

  Christina K. Grecol, Emily A. Sternad, Vonesa Demiri, Nina G. Pukys, Amy Roth, Katherine Kasunick, and Kaili Smith

  The purpose of this investigation was to conduct a systematic review to determine the effectiveness of reading-related phonological processing interventions designed to meet the needs of individuals with complex communication needs (CCN) who require augmentative and alternative communication (AAC). An extensive review of the literature published from 1980 to June of 2018 that included intervention on readingrelated phonological processing skills including phonological awareness (e.g., rhyming, segmentation, blending), letter-sound correspondences, and single-word decoding was conducted using a variety of electronic and table of contents searches. A total of 22 intervention studies ... Read More

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  Environmental Certification Program ISO 14001: A Study of Membership Motivation and Effectiveness

  Lauren Egensperger

  ISO 14001 is an environmental management standard developed by the International Organization of Standardization in 1996. The standard was designed to assist companies with improving environmental performance, enhancing efficiency, and advancing business relations. However, studies suggest that ISO 14001 has experienced varying degrees of success. For this research project, academic literature from environmental journals along with ISO data and annual reports were reviewed. Initially, resources were encountered which propose that the extent to which ISO 14001 improves environmental outcomes remains uncertain due to the presence of symbolic adoption and external ... Read More

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  Effectiveness of Anti-Discrimination Policies: An Analysis of Housing Advertisements

  Brad Dowling

  This project investigates the efficacy of a proposed policy intervention related to housing discrimination. The student designed and executed a python script to collect information from rental housing advertisements in order to assess them for discriminatory language. Looking through apartment rental listings, common information includes number of bedrooms and bathrooms, location, rental cost, and whether the landlord allows pets. It is not uncommon to see the phrase “No Section 8” as well. These advertisements are exhibiting source of income (SOI) discrimination, whereby a landlord does not rent to a prospective ... Read More

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  The Formation of Twitter Networks among U.S. City Mayors

  Sam Motes and Gabrielle Parsson

  This project (a) explores the extent to which mayors use social media to interact with other mayors, (b) identifies the different types of information shared, and (c) examines the factors that influence whether mayors share information. Focusing on the 100 largest cities in the United States by population, we conduct a network analysis of interactions between mayors, occurring on Twitter from 2016-2018. Findings demonstrate an active information network. Types of information shared address city operations, the favorable presentation of a mayor’s city, political positioning, and symbolic acts of congratulations, gratitude, ... Read More

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  Socioeconomic mobility of local refugees: An analysis of Syrian, Congolese and Ukrainian/Russian refugees

  Ahna Mullins

  In FY18, the United States has received 18,214 refugees with Ohio receiving 6.69% of that total, which places Ohio second only to Texas. In partnership with one of largest refugee resettlement agencies in Ohio, this study explored the experiences of refugees from Ukraine, Democratic Republic of the Congo (DRC), and Syria. A literature review, interviews, and mini focus group suggest a diverse set of experiences, yet some common themes. Such themes include a can-do attitude, perseverance, and a long-term orientation towards success. In contrast to refugees from Syria and Ukraine, ... Read More

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  Surface Functionalization of Pure-Chirality Carbon Nanotubes by Covalent and Noncovalent Chemistry

  Fjorela Xhyliu and Niyousha Mohammad Shafie

  Single-wall carbon nanotubes (SWCNTs) are one-dimensional cylindrical nanostructures with distinct electronic and optical properties. With all its atoms on the surface, SWCNTs have been widely explored for chemical modification through noncovalent and covalent chemistry, which can provide promising applications in bioimaging and sensing. Here we investigated surface functionalization of purechirality SWCNTs with various glycopolymers, surfactants, and RPMI cell culture media with and without fetal bovine serum (FBS). Raman, vis-NIR absorption, and vis-NIR fluorescence spectra of SWCNTs in various solvent environments were monitored over time. While nanotube aggregation was not observed ... Read More

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  Treatment of non-epithelial vaginal cells from Lysyl Oxidase like one knockout mice (LOXL 1) with nanoparticles (NPs)

  Priya Patel

  Female pelvic floor dysfunction includes pelvic organ prolapse (POP) due to multiple vaginal births causing elastin strength to be reduced. Several normal functions are compromised including bladder control, fecal continence, and painful urination and many other symptoms. Currently no effective treatment is known and women seek surgical mesh implants to correct these issues which are not entirely safe nor effective. The condition of POP affects women across the world and effective treatment is sought. Varying proteins including lysyl oxidase (LOX), tissue inhibitors of metalloproteinases, and matrix metalloproteinases are involved in ... Read More

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  Multi-phase Waste Gasification – Reaction Engineering for Sustainable Living Environments

  Kristen M. Reyes and Mason J. Lang

  Gasification converts carbon-based (organic) materials into gaseous products typically referred to as synthetic gas. This technology is an alternative for reducing carbon footprint of energy generation as well as for waste management. This research examines Catalytic Gasification as a route to Sustainability while converting spaceflight and municipal waste into high-value products. As polyethylene (PE) makes up one of the largest portions of both municipal and space waste, this project centered its attention on the gasification of mid-density PE. We used a slurry containing middensity PE, water, and solid catalysts (ruthenium ... Read More

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  The role of synthesis solvent in particle size of metal organic frameworks

  Jonathan Krisak

  Metal organic frameworks are a class of nanoporous materials with pore sizes ranging from 0.5 to 3 nm and high surface areas (500-6000 m2/g). These materials have potential applications in industrial catalysis, separation and purification, bio-mimetics, drug delivery, semiconductors, sensors and other electronics. The aim of this study is to understand the role of solvent in control of the particle size of the final MOF product. CuBTC MOF has been used as a model MOF in this study to understand this effect. Altering the dielectric constant of solvents is a ... Read More

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  Characterizing Complexes of DNA and Elastin-like Polypeptides

  Bryce Noe

  Elastin-like polypeptides (ELPs) are a class of environmental responsive materials. When prepared with a protein motif that selectively binds to nucleic acids, a nucleic acid-ELP complex can be formed, conferring the responsive properties of ELP onto the nucleic acid. One possible use for such a complex is in DNA origami, where nanoscaled assemblies of DNA can be transformed into nanomachines by using the ELP as an actuator. Other possible uses include the isolation and extraction of a selected strands of genetic material, or the delivery of genetic material to a ... Read More

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  Methodology Development for the Implementation ofMicrofluidic Mixers

  Tahir Butt and Gautam Mahajan

  Microfluidic platforms have been widely regarded as defining technologies for the development of chemical and biological synthesis and analysis systems, due to benefits associated with reduced reactant consumption, increases by orders of magnitude of the surface-to-volume ratios, and greatly enhanced control over reactions variables such as temperature and pressure. However, one of the bottlenecks for their wide application is the difficulty in achieving mixing, given the typical laminar flows in these systems. In this work we implement experimentally, various strategies using geometrical features to control the fluid motion and induce ... Read More

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  Implementation of a Reverse Staggered-Herringbone Microfluidic Mixer for High-throughput Polymeric Nanoparticles Synthesis

  Alexa Roberts

  The goal of this research is to implement and optimize the operating conditions of a microfluidic mixer to synthesize polymeric nanoparticles (NPs) in a high-throughput fashion. Using a reverse staggered-herringbone microfluidic mixer that we recently designed, the effects of experimental conditions such as flowrate and reactant composition on NP characteristics were investigated and optimized. The device design allowed for physical contact between two streams of fluids – one containing poly(lactic-co-glycolic acid; PLGA) in acetonitrile and the other deionized water, to allow for efficient mixing and NP precipitation to occur. The ... Read More

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  Prediction of Metabolism-Induced Neurotoxicity on a 384PillarPlate

  Rushabh Patel, Pranav Joshi, Soo-Yeon Kang, Stephen Hong, and Parnian Bigdelou

  Metabolism of compounds including neurotoxins primarily occurs in the liver by a variety of drug-metabolizing enzymes (DMEs) followed by a series of downstream responses. Unmodified (or parent) neurotoxins are transported into human hepatocytes through several influx transporters or via passive diffusion and undergo Phase I and Phase II biotransformation by DMEs before they are cleared. Neurotoxins and their metabolites generated from human hepatocytes could potentially lead to the toxic effects on neural stem cells (NSCs) as the reactive metabolites have potential for producing reactive oxygen species (ROS), which can lead ... Read More

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  A 3D Cancer Cell Migration Assay on a 384-Pillar Plate with Sidewalls

  Nicholas Lesh, Alexander Roth, Stephen Hong, Oju Jeon, and Eben Alsberg

  Hepatocellular carcinoma (HCC) is an aggressive liver cancer where prognosis is heavily tied to metastasis progression. Researchers look to determine the triggers for metastasis to control its spread. The goal of this project is to determine these triggers by quantifying Hep3B cell migration on a high-throughput platform. We infected Hep3B cells with lentiviruses containing mCherry to produce stable fluorescent cells. Next, we determined the stability of growth factors in oxidized, methacrylated alginate (OMA) hydrogel by binding growth factors with methacrylated heparin sulfate (MHS) before encapsulating in OMA, printing onto the ... Read More

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  Dendrite Morphology of Pb-5.8 Sb Alloy: Gradient Freeze DS with Cross-Section Area Change

  Michael Shannon

  Directional solidification (DS) is the process of solidifying a metal alloy from one end to another resulting in aligned primary dendrites which are branched tree like features. Alignment of primary dendrites along [100] direction and their uniformity and distribution along the DS length determines the mechanical properties. These properties are especially important for single crystal turbine blade applications in modern gas turbine engines. Convection during solidification plays an important role in formation of detrimental defects, such as, misaligned grains, non-uniformity of dendrites and composition inhomogeneity. In this study the microstructural ... Read More

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  Boundary effects on the locomotion of active Janus particles

  Marola W. Issa and Nicky R. Baumgartner

  Self-propelled or “active” micrometer scale particles are capable of supplying local mechanical work, necessary for microscale cargo delivery and useful in other applications within bioimaging and sensing. Research in the last decade has focused on developing, measuring, and manipulating the locomotion mechanisms of active particles in simple environments. However, many applications will be in complex environments with nearby boundaries or variations in physiochemical cues. This poster reports the directed motion of platinum coated polystyrene particles at infinite dilution in the presence of H2O2, which acts as a fuel to drive ... Read More

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  Civil Engineering Surrounds You

  Claire Anderer-Armstrong

  Academic engineering departments are regularly asked to conduct tours of their laboratories to prospective CSU students. For the Civil & Environmental Engineering department, the tours typically take place in the Driving Simulation laboratory, which houses an RS-600 driving simulator. The purpose of this project was to develop a driving scenario that highlights various aspects of civil engineering. The programmed scenario will be used to conduct future tours.

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  Virtual Reality Based Serious Games for STNA Training

  Ryan Thomas Kall

  In this project, exploratory steps have been taken towards the development of a set of serious games for state tested nursing assistants (STNAs) education and training, which promises to make the training more engaging and effective. Tasks include getting familiar with developing 3D scenes with Unity, human activity recognition with Microsoft Kinect, creating holograms with Microsoft HoloLens, and help implement a gaze-based mechanism for performance assessment in patient transfer skills.

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  Spark Plasma Sintering of Soft magnetic Materials

  Harnavdeep Kaur, Taban Larimian, and Javier Esquivel

  Over the past 3 decades, iron-based soft magnetic alloys such as Finemet (Fe73.5Si13.5B9Nb3Cu1 (at%)) have attracted great interest due to their exceptional magnetic properties like high magnetization, low coercivity, and high curie temperature. However, the production of amorphous precursor requires very high cooling rates, and thus only wires, powders, and thin ribbons are achievable, yet these are not suitable in industrial applications where large volume of bulk magnetic components is required. Mechanical alloying (MA) has gained special attention as a powerful non-equilibrium process for fabricating amorphous and nanocrystalline materials, whereas ... Read More

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  Comparative Study of the Microstructure and Mechanical Properties of Mechanically Alloyed and Spark Plasma Sintered AlxCoCrFeNi (0≤x≤2)High Entropy Alloys

  David Mikhail

  High entropy alloys are a new class of material systems that have promising potential in high temperature structural applications. Mechanical alloying (MA) has gained special attention as a powerful non-equilibrium process for fabricating amorphous and nanocrystalline materials, whereas spark plasma sintering (SPS) is a unique technique for processing dense and near net shape bulk alloys with homogenous microstructure. This research paper discusses novel mechanically alloyed followed by spark plasma sintering approach for assessing composition-microstructure-microhardness relationship in AlxCoCrFeNi (0≤x≤2) high entropy alloy as a candidate system. With increasing Al content, there ... Read More