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Submissions from 2016

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Oncogenic PIK3CA Mutations Reprogram Glutamine Metabolism in Colorectal Cancer, Yujun Hao, Yardena Samuels, Qingling Li, Dawid Krokowski, Bo-Jhih Guan, Chao Wang, Zhicheng Jin, Bohan Dong, Bo Cao, Xiujing Feng, Min Xiang, Claire Xu, Stephen Fink, Neal J. Meropol, and Yan Xu

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Inhibition of Yeast Ribonucleotide Reductase by Sml1 Depends on the Allosteric State of the Enzyme, Tessianna A. Misko, Sanath R. Wijerathna, Tomas Radivoyevitch, Anthony J. Berdis, Md. Faiz Ahmad, Michael E. Harris, and Chris G. Dealwis

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Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma, Sergei Vatolin, James G. Phillips, Babal K. Jha, Shravya Govindgari, Jennifer Hu, Dale Grabowski, Yvonne Parker, Daniel J. Lindner, Fei Zhong, Clark W. Distelhorst, Mitchell R. Smith, Claudiu Cotta, Yan Xu, Sujatha Chilakala, Rebecca R. Kuang, Samantha Tall, and Frederic J. Reu

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Manganese Functionalized Graphene As a New Platform for Peroxynitrite Sensing, Haitham F. Kalil and Mekki Bayachou

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Early Growth and Development Impairments in Patients with Ganglioside GM3 Synthase Deficiency, H. Wang, A. Wang, Dan Wang, A. Bright, V. Sency, Aimin Zhou, and B. Xin

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Preparation of Chain-End Clickable Recombinant Protein and its Bio-Orthogonal Modification, Lin Wang, Rui Jiang, Lin Wang, Yang Liu, and Xue-Long Sun

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Metabolomics Reveals New Mechanisms for Pathogenesis in Barth Syndrome and Introduces Novel Roles for Cardiolipin in Cellular Function, Yana Sandlers, Kelly Mercier, Wimal Pathmasiri, Jim Carlson, Susan McRitchie, Susan Sumner, and Hilary J. Vernon

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A Systematic Investigation of Structure/Function Requirements for The Apolipoprotein A-I/Lecithin Cholesterol Acyltransferase Interaction Loop of High-density Lipoprotein, Xiaodong Gu, Zhiping Wu, Ying Huang, Matthew A. Wagner, Camelia Baleanu Gogonea, Ryan A. Mehl, Jennifer A. Buffa, Anthony J. DiDonato, Leah B. Hazen, Paul L. Fox, Valentin Gogonea, John S. Parks, Joseph A. DiDonato, and Stanley L. Hazen

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Structural Optimization of Non-Nucleoside DNA Methyltransferase Inhibitor as Anti-Cancer Agent, Bo Zhong, Sergei Vatolin, Nethrie D. Idippily, Rati Lama, Laila A. Alhadad, Frederic J. Reu, and Bin Su

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Preparation and Structures of Two Mixed-Ligand 4-methylpyridine Indium Bromide Complexes, John Masnovi, Eric B. Clark, Aloysius F. Hepp, John D. Schupp, and Philip E. Fanwick

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Identification of Critical Paraoxonase 1 Residues Involved in High Density Lipoprotein Interaction, Xiaodong Gu, Ying Huang, Bruce S. Levison, Gary Gerstenecker, Anthony J. DiDonato, Leah B. Hazen, Joonsue Lee, Valentin Gogonea, Joseph A. DiDonato, and Stanley L. Hazen

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The Dual Regulatory Role of Amino Acids Leu480 and Gln481 of Prothrombin, Joesph R. Wiencek, Jamila Hirbawi, Vivien C. Yee, and Michael Kalafatis

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Synthesis of an End-to-End Protein–Glycopolymer Conjugate via Bio-Orthogonal Chemistry, Hailong Zhang, Jacob Weingart, Valentinas Gruzdys, and Xue-Long Sun

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Indomethacin Derivatives as Tubulin Stabilizers to Inhibit Cancer Cell Proliferation, Snigdha Chennamaneni, Chunfang Gan, Rati Lama, Bo Zhong, and Bin Su

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Orally Active and Selective Tubulin Inhibitors as Anti-Trypanosome Agents, Vishal Nanavaty, Rati Lama, Ranjodh Sandhu, Bo Zhong, Daniel Kulman, Viharika Bobba, Anran Zhao, Bibo Li, and Bin Su

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Structural Insights Into High Density Lipoprotein: Old Models and New Facts, Valentin Gogonea

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Methods of Peroxynitrite Synthesis in the Context of the Development and Validation of Peroxynitrite Sensors, Mekki Bayachou, Ghaith Altawallbeh, Haitham F. Kalil, Sarah Wojciechowski, and Tiyash Bose

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Chapter 7 – Chemotherapeutic Intervention by Inhibiting DNA Polymerases, A. Dasari, Jung-Suk Choi, and Anthony J. Berdis

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Determination of MLN0128, An Investigational Antineoplastic Agent, in Human Plasma by LC–MS/MS, Sandeep R. Kunati and Yan Xu

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Measurement of Ring Strain Using Butanols: A Physical Chemistry Lab Experiment, William R. Martin, Ada S. Davidson, and David W. Ball

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Sialyltransferase Inhibition and Recent Advances, Libo Wang, Ying Liu, Lijun Wu, and Xue-Long Sun

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TMCO1 Is an ER Ca2+ Load-Activated Ca2+ Channel, Qiao-Chu Wang, Qiaoxia Zheng, Haiyan Tan, Bing Zhang, Xiaoling Li, Yuxiu Yang, Jie Yu, Yang Liu, Hao Chai, Xi Wang, Zhongshuai Sun, Jiu-Qiang Wang, Shu Zhu, Fengli Wang, Maojun Yang, Caixia Guo, Heng Wang, Qingyin Zheng, Yang Li, Quan Chen, Aimin Zhou, and Tie-Shan Tang

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Targeting Radioresistant Breast Cancer Cells by Single Agent CHK1 Inhibitor via Enhancing Replication Stress, Yao Zhang, Jinzhi Lai, Zhanwen Du, Jinnan Gao, Shuming Yang, Shashank Gorityala, Xiahui Xiong, Ou Deng, Zhefu Ma, Chunhong Yan, Gonzalo Susana, Yan Xu, and Junran Zhang

Submissions from 2015

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Structural Characterization of Copper–Indium Chalcopyrite Precursors (PPh3)2CuIn(ER)4 [R=CH3, E=S and R=Ph, E=S and Se], John Masnovi, Kulbinder K. Banger, Philip E. Fanwick, and Aloysius F. Hepp

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Oriented Immobilized Sialyloligo-macroligand Microarray, Satya Nandana Narla and Xue-Long Sun

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Multi-dimensional Glycan Microarrays with Glyco-macroligands, Satya Nandana Narla, Huan Nie, Yu Li, and Xue-Long Sun

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Effects of Interferons and Double-Stranded RNA on Human Prostate Cancer Cell Apoptosis, Haiyan Tan, Chun Zeng, Junbo Xie, Norah J. Alghamdi, Ya Song, Hongbing Zhang, Aimin Zhou, and Di Jin

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Determination of Triapine, A Ribonucleotide Reductase Inhibitor, In Human Plasma by Liquid Chromatography Tandem Mass Spectrometry, Ye Feng, Charles A. Kunos, and Yan Xu

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Globally Profiling Sialylation Status of Macrophages Upon Statin Treatment, Dan Wang, Huan Nie, Evgeny Ozhegov, Lin Wang, Aimin Zhou, Yu Li, and Xue Long Sun

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Sensitization of TRAIL-Resistant Malignant Melanomas by Ellagic Acid, Katherine A. Turner, Daniel Lindner, and Michael Kalafatis

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DFT/QTAIM Analysis of the Effect of Late Transition Metal Doping on Methane Selectivity in Fischer–Tröpsch Catalysis, Peter C. Psarras and David W. Ball

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Synthesis and Biological Evaluation of Thiabendazole Derivatives as Anti-Angiogenesis and Vascular Disrupting Agents, Chao Zhang, Bo Zhong, Simin Yang, Liangkun Pan, Siwang Yu, Zhongjun Li, Shuchun Li, Bin Su, and Xiangbao Meng

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Peroxynitrite Sensing: From Graphene-Based Platforms to Modified Boron-Doped Diamond Electrodes, Mekki Bayachou and Haitham F. Kalil

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In Vitro and In Vivo Evaluation of Tubulin Inhibitors with Non-Small Cell Lung Cancer Pre-Clinical Models, Rati Lama, Danting Liu, Bo Zhong, David Danielpour, Aimin Zhou, and Bin Su

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A Rapid LC-MS/MS Method for Quantification of CSUOH0901, a Novel Antitumor Agent, in Rat Plasma, Ramakrishna R. Voggu, Ravali Alagandula, Xiang Zhou, Bin Su Ph.D., Bo Zhong, and Baochuan Guo

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A Rapid LC-MS/MS Method for Quantification of CSUOH0901, A Novel Antitumor Agent, in Rat Plasma, Ramakrishna R. Voggu, Ravali Alagandula, Xiang Zhou, Bin Su, Bo Zhong, and Baochuan Guo

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Crystal Structure of 9-methacryloylanthracene, Aditya Agrahari, Patrick O. Wagers, Steven M. Schildcrout, John Masnovi, and Wiley J. Youngs

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Incorporation of Azide Functionality into Recombinant Protein via Recombinant, Enzymatic, and Chemical Approaches for Bio-Orthogonal Modification, Lin Wang, Rui Jiang, Lin Wang, and Xue-Long Sun

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Aminonitronaphthalenes as Possible High Energy Density Materials, Rebecca J. Murawski and David W. Ball

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Specific N-glycans of Hepatocellular Carcinoma Cell Surface and the Abnormal Increase of Core-α-1, 6-fucosylated Triantennary Glycan via N-acetylglucosaminyltransferases-IVa Regulation, Huan Nie, Xia Liu, Yubao Zhang, Tingting Li, Chao Zhan, Wenjuan Huo, Anshun He, Yuanfei Yao, Yu Jin, Youpeng Qu, Xue-Long Sun, and Yu Li

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A Simple and Rapid LC-MS/MS Method for The Determination of BMCL26 A Novel Anti-Parasitic Agent in Rat Plasma, Ramakrishna R. Voggu, Xiang Zhou, Bing Su, and Baochuan Guo

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Glyco-Functionalized Liposomes, Jacob J. Weingart, Pratima Vabbilisetty, and Xue-Long Sun

Submissions from 2014

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Distinct Conformational Behaviors of Four Mammalian Dual-Flavin Reductases (Cytochrome P450 Reductase, Methionine Synthase Reductase, Neuronal Nitric Oxide Synthase, Endothelial Nitric Oxide Synthase) Determine Their Unique Catalytic Profiles, Mohammad Mahfuzul Haque, Mekki Bayachou, Jesus Tejero, Claire T. Kenney, Naw M. Pearl, Sang-Choul Im, Lucy Waskell, and Dennis J. Stuehr

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Bioassay Guided Identification of Small Chaperone Proteins α-crystallin and Hsp27 Inhibitors from Copaiba Oil, Rati Lama, Bo Zhong, Daniel G. Kulman, and Bin Su Ph.D.

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RNase L Contributes to Experimentally Induced Type 1 Diabetes Onset in Mice, Chun Zeng, Xin Yi, Danny Zipris, Hongli Liu, Lin Zhang, Qiaoyun Zheng, Krishnamurthy Malathi, Ge Jin, and Aimin Zhou

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P101 – Endothelial Nitric Oxide Synthase (eNOS) on Lipid Nanodiscs: Toward A Soluble Assembly Reflecting Native-Like Function of eNOS, Ghaith Altawallbeh, Chris Verdi, Mohammad Mahfuzul Haque, Dennis Stuehr, and Mekki Bayachou

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P105 – Enzyme-Based Nitric Oxide Releasing Thin Films and Fibers, Mekki Bayachou, Bhagya Gunesekera, and Gary Wnek

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Oral 1832-2 – Charge Pairing and Phosphorylation Regulate The Conformational Equilibrium and Switching Rates in Neuronal and Endothelial NO Synthase Flavoprotein Domains, Mohammad Mahfuzul Haque, Sougata Sinha Ray, Mekki Bayachou, and Dennis Stuehr

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P142 – Graphene-Based Nanostructured Interfaces for Selective and Sensitive Peroxynitrite Detection, Haitham Kalil and Mekki Bayachou

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P197 – Sensitive and Selective Electrochemical NO Sensors Modified with Nanostructured Catalyst: Towards Probing The Role of NO in Cystic Fibrosis Pathophysiology, Bose Tiyash, Thomas Bomberger, and Mekki Bayachou

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RNase L Interacts with Filamin A To Regulate Actin Dynamics and Barrier Function for Viral Entry, Krishnamurthy Malathi; Mohammad Adnan Siddiqui; Shubham Dayal; Merna Naji; Heather J, Ezelle; Chun Zeng; Aimin Zhou; and Bret A. Hassel

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Cryoprotective Effect of l-Carnitine on Motility, Vitality and DNA Oxidation of Human Spermatozoa, S. Banihani, A. Agarwal, R. Sharma, and Mekki Bayachou

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Metabolomics of ApcMin/+ Mice Genetically Susceptible to Intestinal Cancer, Jean Eudes J. Dazard, Yana Sandlers, Stephanie K. Doerner, Nathan A. Berger, and Henri Brunengraber

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A New Liquid Chromatography/Tandem Mass Spectrometry Method for Quantification of Gangliosides in Human Plasma, Qianyang Huang, Xiang Zhou, Danting Liu, Baozhong Xin, Karen Cechner, Heng Wang, and Aimin Zhou

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Lead Optimization of Dual Tubulin and Hsp27 Inhibitors, Bo Zhong, Rati Lama, Daniel G. Kulman, Bibo Li Ph.D., and Bin Su Ph.D.

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Development and Validation of LC–MS/MS Method for Quantitative Determination of (−)-Securinine in Mouse Plasma, Simuli L. Wabuyele, David Wald, and Yan Xu

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Reclaiming The Efficacy of β-Lactam–β-Lactamase Inhibitor Combinations: Avibactam Restores The Susceptibility of CMY-2-Producing Escherichia Coli to Ceftazidime, Krisztina M. Papp-Wallace, Marisa L. Winkler, Julian A. Gatta, Magdalena A. Taracila, Sujatha Chilakala, Yan Xu, J. Kristie Johnson, and Robert A. Bonomo

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Mediatorless Immunoassay with Voltage-Controlled Intrinsic Amplification for Ultrasensitive and Rapid Detection of Microorganism Pathogens, Jiapeng Wang, Yan Xu, and Siu Tang Yau

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Site-Specific Nitration of Apolipoprotein A-I at Tyrosine 166 Is Both Abundant within Human Atherosclerotic Plaque and Dysfunctional, Joseph A. DiDonato, Kulwant Aulak, Ying Huang, Matthew A. Wagner, Gary Gerstenecker, Celalettin Topbas, Valentin Gogonea, Anthony J. DiDonato, W.H. Wilson Tang, Ryan A. Mehl, Paul L. Fox, Edward F. Plow, Jonathan D. Smith, Edward A. Fisher, and Stanley L. Hazen

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Lead Optimization of HMBA to Develop Potent HEXIM1 Inducers, Bo Zhong, Rati Lama, Wannarasmi Ketchart, Monica M. Montano, and Bin Su

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An Abundant Dysfunctional Apolipoprotein A1 in Human Atheroma, Ying Huang, Joseph A. DiDonato, Bruce S. Levison, Dave Schmitt, Lin Li, Yuping Wu, Jennifer Buffa, Timothy Kim, Gary S. Gerstenecker, Xiaodong Gu, Chandra S. Kadiyala, Zeneng Wang, Miranda K. Culley, Jennie E. Hazen, Anthony J. DiDonato, Xiaoming Fu, Stela Z. Berisha, Daoquan Peng, Truc T. Nguyen, Shaohong Liang, Chia-Chi Chuang, Leslie Cho, Edward F. Plow, Paul L. Fox, Valentin Gogonea, W.H. Wilson Tang, John S. Parks, Edward A. Fisher, Jonathan D. Smith, and Stanley L. Hazen

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Liposome Surface Functionalization Based on Different Anchoring Lipids via Staudinger Ligation, Pratima Vabbilisetty and Xue-Long Sun

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BSA–Boronic Acid Conjugate as Lectin Mimetics, Satya Nandana Narla, Poornima Pinnamaneni, Huan Nie, Yu Li, and Xue-Long Sun

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Development of A Liquid Chromatographic Method for Quantitative Determination of Triapine, A Ribonucleotide Reductase Inhibitor, by Spectrophotometric Study of Triapine Complexation Reaction, Ye Feng, Melissa McCulloch, and Yan Xu

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Glyco-modification of Protein with O-cyanate Chain-end Functionalized Glycopolymer via Isourea Bond Formation, Valentinas Gruzdys, Hailong Zhang, and Xue-Long Sun

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Synthesis and Evaluation of Some New Aza-B-Homocholestane Derivatives as Anticancer Agents, Yanmin Huang, Jianguo Cui, Sijing Chen, Qifu Lin, Huacan Song, Chunfang Gan, Bin Su, and Aimin Zhou

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Metabolomic Analysis of Liver Tissue From the vx2 Rabbit Model of Secondary Liver Tumors, R. Ibarra, J. E. Dazard, Y. Sandlers, F. Rehman, R. Abbas, R. Kombu, G. F. Zhang, H. Brunengraber, and J. Sanabria

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A Kinetic Analysis of The Inhibition of FOX-4 β-Lactamase, A Plasmid-Mediated AmpC Cephalosporinase, By Monocyclic β-lactams and Carbapenems, Krisztina M. Papp-Wallace, Susana Mallo, Christopher R. Bethel, Magdalena A. Taracila, Andrea M. Hujer, Ana Fernandez, Julian A. Gatta, Kerri M. Smith, Yan Xu, Malcolm G.P. Page, Eric Desarbre, German Bou, and Robert A. Bonomo

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Clinical Laboratory Studies in Barth Syndrome, Hilary J. Vernon, Yana Sandlers, Rebecca McClellan, and Richard I. Kelley

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Quantification of Free Sialic Acid in Human Plasma through a Robust Quinoxalinone Derivatization and LC–MS/MS Using Isotope-labeled Standard Calibration, Dan Wang, Xiang Zhou, Lin Wang, Sihe Wang, and Xue-Long Sun

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Systematic Investigation of Quinoxaline Derivatization of Sialic Acids and Their Quantitation Applicability Using High Performance Liquid Chromatography, Libo Wang, Dan Wang, Xiang Zhou, Lijun Wu, and Xue-Long Sun

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Primary Arylamine-based Tyrosine-targeted Protein Modification, Lin Wang, Valentinas Gruzdys, Nan Pang, Fanhao Meng, and Xue-Long Sun

Submissions from 2013

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Amino Acid Region 1000–1008 of Factor V Is a Dynamic Regulator for the Emergence of Procoagulant Activity, Joesph R. Wiencek, Mahesheema Na, Jamila Hirbawi, and Michael Kalafatis

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β-Lactamase Inhibition by 7-Alkylidenecephalosporin Sulfones: Allylic Transposition and Formation of An Unprecedented Stabilized Acyl-Enzyme, Elizabeth A. Rodkey, David C. Mcleod, Christopher R. Bethel, Kerri M. Smith, Yan Xu, Weirui Chai, Tao Che, Paul R. Carey, Robert A. Bonomo, Focco van den Akker, and John D. Buynak

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Lack of RNase L Attenuates Macrophage Functions, Xin Yi, Chun Zeng, Hongli Liu, Xiaoli Chen, Ping Zhang, Boo Seok Yun, Ge Jin, and Aimin Zhou

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Can Inhibitor-Resistant Substitutions in The Mycobacterium Tuberculosis β-Lactamase BlaC Lead to Clavulanate Resistance?: A Biochemical Rationale for The Use of β-Lactam–β-Lactamase Inhibitor Combinations, Sebastian G. Kurz, Kerstin A. Wolff, Saugata Hazra, Christopher R. Bethel, Andrea M. Hujer, Kerri M. Smith, Yan Xu, Lee W. Tremblay, John S. Blanchard, Liem Nguyen, and Robert A. Bonomo

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Cyclometalated Iridium(III) Complexes with Deoxyribose Substituents, Ayan Maity, Jung-Suk Choi, Thomas S. Teets, Nihal Deligonul, Anthony J. Berdis, and Thomas G. Gray

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A Comparative Study of Antitumor Activities and DNA Cleavage On A Class of Dehydroabietylamine Derivatives, Chao Xiang Liu, Zhong Xiang Lin, Xing Yu, Zhou Lu, Aimin Zhou, and Yong Li Bao

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Function and Distribution of Apolipoprotein A1 in The Artery Wall Are Markedly Distinct From Those in Plasma, Joseph A. DiDonato, Ying Huang, Kulwant S. Aulak, Orli Even-Or, Gary Gerstenecker, Valentin Gogonea, Yuping Wu, Paul L. Fox, W.H. Wilson Tang, Edward F. Plow, Jonathan D. Smith, Edward A. Fisher, and Stanley L. Hazen

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Myeloperoxidase, Paraoxonase-1, and HDL Form A Functional Ternary Complex, Ying Huang, Zhiping Wu, Meliana Riwanto, Shengqiang Gao, Bruce S. Levison, Xiaodong Gu, Xiaoming Fu, Matthew A. Wagner, Christian Besler, Gary Gerstenecker, Renliang Zhang, Xin Min Li, Anthony J. DiDonato, Valentin Gogonea, W.H. Wilson Tang, Jonathan D. Smith, Edward F. Plow, Paul L. Fox, Diana M. Shih, Aldons J. Lusis, Edward A. Fisher, Joseph A. DiDonato, Ulf Landmesser, and Stanley L. Hazen

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Thermodynamic Characterization of Five Key Kinetic Parameters That Define Neuronal Nitric Oxide Synthase Catalysis, Mohammad Mahfuzul Haque, Jesus Tejero, Mekki Bayachou, Zhi-Qiang Wang, Mohammed Fadlalla, and Dennis J. Stuehr

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Membrane Mimetic Surface Functionalization of Nanoparticles: Methods and Applications, Jacob Weingart, Pratima Vabbilisetty, and Xue-Long Sun

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Development and Characterization of A Non-natural Nucleoside that Displays Anticancer Activity Against Solid Tumors, Jackelyn Golden, Edward A. Motea, Xuemei Zhang, Jung-Suk Choi, Ye Feng, Yan Xu, Irene Lee, and Anthony J. Berdis

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Inhibition of Metastasis by HEXIM1 Through Effects on Cell Invasion and Angiogenesis, W. Ketchart, Kerri M. Smith, T. Krupka, B. M. Wittmann, Y. Hu, P. A. Rayman, Y. Q. Doughman, J. M. Albert, X. Bai, J. H. Finke, Yan Xu, A. A. Exner, and M. M. Montano

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Synthesis and Anticancer Mechanism Investigation of Dual Hsp27 and Tubulin Inhibitors, Bo Zhong, Snigdha Chennamaneni, Rati Lama, Xin Yi, Werner J. Geldenhuys, John J. Pink, Afshin Dowlati, Yan Xu, Aimin Zhou, and Bin Su Ph.D.

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Synthesis and Anticancer Mechanism Investigation of Dual Hsp27 and Tubulin Inhibitors, Bo Zhong, Snigdha Chennamaneni, Rati Lama, Xin Yi, Werner J. Geldenhuys, John J. Pink, Afshin Dowlati, Yan Xu, Aimin Zhou, and Bin Su

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Logger Rhythm, David W. Ball

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A Phase 1 Study of TRC102, An Inhibitor of Base Excision Repair, and Pemetrexed in Patients with Advanced Solid Tumors, Michael S. Gordon, Lee S. Rosen, David Mendelson, Ramesh K. Ramanathan, Jonathan Goldman, Lili Liu, Yan Xu, Stanton L. Gerson, Stephen P. Anthony, William D. Figg, Shawn Spencer, Bonne J. Adams, Charles P. Theuer, Bryan R. Leigh, and Glen J. Weiss

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Polymerized Hemin as An Electrocatalytic Platform for Peroxynitrite's Oxidation and Detection, Serban F. Peteu, Tiyash Bose, and Mekki Bayachou

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The Low-Resolution Structure of Nascent High Density Lipoprotein Reconstituted with DMPC With and Without Cholesterol Reveals A Mechanism for Particle Expansion, Valentin Gogonea, Gary S. Gerstenecker, Zhiping Wu, Xavier Lee, Celalettin Topbas, Matthew A. Wagner, Thomas C. Tallant, Jonathan D. Smith, Phil Callow, Vitaliy Pipich, Helen Malet, Guy Schoehn, Joseph A. DiDonato, and Stanley L. Hazen

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Why is the Sky Blue?, James A. Locke and David W. Ball

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Bio-Inspired Liposomal Thrombomodulin Conjugate through Bio-Orthogonal Chemistry, Hailong Zhang, Jacob Weingart, Rui Jiang, Jianhao Peng, Qingyu Wu, and Xue-Long Sun

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Insights Into The Roles of Desolvation and π-Electron Interactions During DNA Polymerization, Edward A. Motea, Irene Lee, and Anthony J. Berdis

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Development, Validation and Pilot Screening of An In Vitro Multi-Cellular Three-Dimensional Cancer Spheroid Assay for Anti-Cancer Drug Testing, Rati Lama, Lin Zhang, Janine M. Naim, Jennifer Williams, Aimin Zhou, and Bin Su

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Design and Exploration of Novel Boronic Acid Inhibitors Reveals Important Interactions with A Clavulanic Acid-Resistant Sulfhydryl-Variable (SHV) β-Lactamase, Marisa L. Winkler, Elizabeth A. Rodkey, Magdalena A. Taracila, Sarah M. Drawz, Christopher R. Bethel, Krisztina M. Papp-Wallace, Kerri M. Smith, Yan Xu, Jeffrey R. Dwulit-Smith, Chiara Romagnoli, Emilia Caselli, Fabio Prati, Focco van den Akker, and Robert A. Bonomo

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Wien’s Displacement Law as a Function of Frequency, David W. Ball

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Time Course of Hepatic Gluconeogenesis During Hindlimb Suspension Unloading, Ilya R. Bederman, Visvanathan Chandramouli, Yana Sandlers, Leigh Henderson, and Marco E. Cabrera

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Spectroscopic Analysis of Polymerization and Exonuclease Proofreading By A High-Fidelity DNA Polymerase During Translesion DNA Synthesis, Babho Devadoss, Irene Lee, and Anthony J. Berdis

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Charge-Pairing Interactions Control The Conformational Setpoint and Motions of The FMN Domain in Neuronal Nitric Oxide Synthase, Mohammad Mahfuzul Haque, Mekki Bayachou, Mohammed A. Fadlalla, Deborah Durra, and Dennis J. Stuehr

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Synthesis and Evaluation of Some 17-Acetamidoandrostane and N,N-Dimethyl-7-deoxycholic Amide Derivatives as Cytotoxic Agents: Structure/Activity Studies, Yanmin Huang, Jianguo Cui, Linyi Jia, Chunfang Gan, Huacan Song, Chun Zeng, and Aimin Zhou